2014 Publications

 

1 Stereoselective Construction of 1β-Azide- and 1β-Cyano-2-deoxyribose Derivatives
Hiromichi Fujioka, Takahiro Moriya, Kazuhisa Okamoto, Yutaka Minamitsuji, Yoshifumi Ueyama, Nao Matsumoto, and Kenichi Murai
Heterocycles in press (DOI: 10.3987/COM-14-S(K)86)
2 Selective Transformations of Carbonyl Functions in the Presence of α,​β-​Unsaturated Ketones: Concise Asymmetric Total Synthesis of Decytospolides A and B
Yahata, Kenzo; Minami, Masaki; Watanabe, Kei; Fujioka, Hiromichi
Organic Letters (2014), 16(14), 3680-3683.ol-2014-01463p_0007
3 C3-​Symmetric chiral trisimidazoline-​catalyzed Friedel-​Crafts (FC)​-​type reaction
Takizawa, Shinobu; Hirata, Shuichi; Murai, Kenichi; Fujioka, Hiromichi; Sasai, Hiroaki
Organic & Biomolecular Chemistry (2014), 12(31), 5827-5830.
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4 Enantioselective iodolactonization of allenoic acids
Murai, Kenichi; Shimizu, Nozomi; Fujioka, Hiromichi
Chem. Commun. 2014, 50, 12530-12533.
Graphical abstract: Enantioselective iodolactonization of allenoic acids
5 Enantioselective, Desymmetrizing, Bromolactonization Reactions of Symmetric Olefinic Dicarboxylic Acids
Kenichi Murai, Junki Nakajima, Akira Nakamura, Norimichi Hyogo, Hiromichi Fujioka
Chem. Asian. J. (2014), 9, 3511-3517.Thumbnail image of graphical abstract
6 Selective Formation of Trans​/threo​/cis and Cis​/threo​/cis Bis-​tetrahydrofurans from the Same Diene Diols
Fujioka, Hiromichi; Oki, Tomohiro; Hayashi, Tatsuya; Yamakawa, Maki; Kurachi, Takeshi; Nakahara, Kenji; Maehata, Ryota; Hamada, Tomohito; Murai, Kenichi; Kita, Yasuyuki
Heterocycles (2014), 88(2), 1323-1336.
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7 Rational hopping of a peptidic scaffold into non-peptidic scaffolds: structurally novel potent proteasome inhibitors derived from a natural product, belactosin A
Shuhei Kawamura, Yuka Unno, Takatsugu Hirokawa, Akira Asai, Mitsuhiro Arisawa and Satoshi Shuto
Chem. Commun.  (2014), 50, 2445-2447.Graphical abstract: Rational hopping of a peptidic scaffold into non-peptidic scaffolds: structurally novel potent proteasome inhibitors derived from a natural product, belactosin A
8 Structurally Novel Highly Potent Proteasome Inhibitors Created by the Structure-Based Hybridization of Non-Peptidic Belactosin Derivatives and Peptide Boronates
Shuhei Kawamura, Yuka Unno, Akira Asai, Mitsuhiro Arisawa and Satoshi Shuto
J. Med. Chem. (2014), 57, 2726-2735.Abstract Image
9 Palladium-Nanoparticle-Catalyzed Direct Ethynylation of Aliphatic Carboxylic Acid Derivatives via C(sp3)–H Bond Functionalization
Mohammad Al-Amin, Mitsuhiro Arisawa, Satoshi Shuto, Yusuke Ano, Mamoru Tobisu and Naoto Chatani
Adv. Synth. Catal. (2014), 356, 1631-1637.Link to full-size graphical abstract
10 Ligand-free Suzuki-Miyaura Coupling with Sulfur-modified Gold-supported Palladium in the Synthesis of a Conformationally-Restricted Cyclopropane Compound Library with Three-Dimensional Diversity
Mitsuhiro Arisawa, Takatoshi Sato, Naoyuki Hoshiya, Mohammad Al-Amin, Yuji Kogami and Satoshi Shuto
ACS Combi. Sci. (2014), 16, 215-220.Abstract Image
11 Palladium-Nanoparticle-Catalyzed 1,7-Palladium Migration Involving C-H Activation, Followed by Intramolecular Amination: Regioselective Synthesis of N1-Arylbenzotriazoles and an Evaluation of Their Inhibitory Activity Towards Indoleamine 2,3-Dioxygenase
Koji Takagi, Mohammad Al-Amin, Naoyuki Hoshiya, Johan Wouters, Hiroshi Sugimoto, Yoshitsugu Shiro, Hayato Fukuda, Satoshi Shuto, Mitsuhiro Arisawa
J. Org. Chem. (2014), 79, 6366-6371.Abstract Image
12 Development of a New Class of Proteasome Inhibitors with an Epoxyketone Warhead: Rational Hybridization of Non-peptidic Belactosin Derivatives and Peptide Epoxyketones
Shuhei Kawamura, Yuka Unno, Akira Asai, Mitsuhiro Arisawa, Satoshi Shuto
Bioorg. Med. Chem. (2014), 22, 3091-3095.image
13 Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor
Takaaki Kobayashi, Akihiro Suemasa, Arisaw Igawa, Soichiro Ide, Hayato Fukuda, Hiroshi Abe, Mitsuhiro Arisawa, Masabumi Minami, Satoshi Shuto
ACS Med. Chem. Lett. (2014),  in pressFigure

 

総説

1 In situ protection methodology in carbonyl chemistry
Yahata, Kenzo; Fujioka, Hiromichi
Chemical & Pharmaceutical Bulletin (2014), 62(1), 1-11.