| I. | Paper |
| 1 | Pd/TiO2-Photocatalyzed Self-Condensation of Primary Amines To Afford Secondary Amines at Ambient Temperature Lyu-Ming Wang, Kensuke Kobayashi, Mitsuhiro Arisawa, Susumu Saito,* Hiroshi Naka* Org. Lett. 2019, 21, 341–344. DOI:10.1021/acs.orglett.8b03271  |
| 2 | Design and Synthesis of N1,N8-Diacetylspermidine Analogues having a Linker with Desired Functional Groups Reiya Ohta, Akihiro Oguro, Kazuhiro Nishimura, Kenichi Murai, Hiromichi Fujioka, Mitsuhiro Arisawa* Org. Biomol. Chem. 2019, 17, 867-875. DOI:10.1039/C8OB02900H  |
| 3 | Tricarboxylic acid cycle activity suppresses acetylation of mitochondrial proteins during early embryonic development in Caenorhabditis elegans Kazumasa Hada, Keiko Hirota, Ai Inanobe, Koichiro Kako, Mai Miyata, Sho Araoi, Masaki Matsumoto, Reiya Ohta, Mitsuhiro Arisawa, Hiroaki Daitoku, Toshikatsu Hanada, and Akiyoshi Fukamizu J. Biol. Chem. 2019, 294, 3091–3099. DOI:10.1074/jbc.RA118.004726 |
| 4 | Chemoselective Nucleophilic Functionalizations of Aromatic Aldehydes and Acetals via Pyridinium Salt Intermediates Takahiro Kawajiri, Maho Kato, Hiroki Nakata, Ryota Goto, Shin-yo Aibara, Reiya Ohta, Hiromichi Fujioka, Hironao Sajiki, and Yoshinari Sawama J. Org. Chem. 2019, 84, 3853–3870. DOI:10.1021/acs.joc.8b02965  |
| 5 | Metal-Free Nitrogen-Containing Polyheterocyclic Near-Infrared (NIR) Absorption Dyes: Synthesis, Absorption Properties, and Theoretical Calculation of Substituted 5-Methylisoindolo[2,1-a]quinolines Yuki Fujii, Yukinori Suwa, Yuki Wada, Tsunayoshi Takehara, Takeyuki Suzuki, Yusuke Kawashima, Norihito Kawashita, Tatsuya Takagi, Hiromichi Fujioka, Mitsuhiro Arisawa ACS Omega 2019, 4, 5064-5075. DOI:10.1021/acsomega.9b00315  |
| 6 | Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors HidenobuMurafuji, Tsuyoshi Muto, Megumi Goto, Seiichi Imajo, Hajime Sugawara, Yoshiaki Oyama, Yutaka Minamitsuji, Shuji Miyazaki, Kenichi Murai, Hiromichi Fujioka Bioorganic & Medicinal Chemistry Letters, 2019, 29, 334-338. DOI: 10.1016/j.bmcl.2018.11.011  |
| 7 | Oxidative Rearrangement of Primary Amines Using PhI(OAc)2 and Cs2CO3 Wataru Yamakoshi, Mitsuhiro Arisawa, Kenichi Murai* Org. Lett. 2019, 21, 3023–3027. DOI: 10.1021/acs.orglett.9b00559  |
| 8 | Chemoselective Transformations of Aromatic Methoxymethyl Ethers Using Trialkylsilyl Triflate and 2,2’-Bipyridyl Mizushi Yanagihara, Reiya Ohta, Kenichi Murai, Mitsuhiro Arisawa, Hiromichi Fujioka ACS Omega 2019, 4, 8465-8471. DOI: 10.1021/acsomega.9b00643  |
| 9 | Pd-catalyzed Migratory Cycloisomerization of N-Allyl-o-allenylaniline Derivatives Yasuhiro Ii, Satoru Hirabayashi, Shohei Yoshioka, Hiroshi Aoyama, Kenichi Murai, Hiromichi Fujioka, Mitsuhiro Arisawa Org. Lett. 2019, 21, 3501-3504. DOI: 10.1021/acs.orglett.9b00676  |
| 10. | Ligand-free Suzuki–Miyaura coupling reaction of aryl chloride using a continuous irradiation type microwave and palladium nanoparticle catalyst: Effect of a co-existing solid Makito Yamada, Yasunori Shio, Toshiki Akiyama, Tetsuo Honma, Yuuta Ohki, Naoyuki Takahashi, Kenichi Murai, Mitsuhiro Arisawa Green Chem. 2019, 21, 4541-4549. DOI: 10.1039/C9GC01043B  |
| 11 | SF3B2-mediated RNA splicing drives human prostate cancer progression Norihiko Kawamura, Keisuke Nimura, Kotaro Saga, Airi Ishibashi, Koji Kitamura, Hiromichi Nagano, Yusuke Yoshikawa, Kyoso Ishida, Norio Nonomura, Mitsuhiro Arisawa, Jun Luo, and Yasufumi Kaneda Cancer Res. 2019, 79, 5204-5417. DOI: 10.1158/0008-5472.CAN-18-3965  |
| 12 | Nickel Nanoparticle-Catalyzed Carboxylation of Unsaturated Hydrocarbon with CO2 Using Sulfur-Modified Au-Supported Nickel Material Takahisa Taniguchi, Nozomi Saito, Ryohei Doi, Arato Kimoto, Naoyuki Hoshiya, Katsumasa Fujiki, Satoshi Shuto, Hiromichi Fujioka, Mitsuhiro Arisawa,* and Yoshihiro Sato* Chem. Lett. 2019, 48, 1406–1409. DOI: org/10.1246/cl.190650  |
| 13 | Ni-Catalyzed Cycloisomerization between 3‐Phenoxy Acrylic Acid Derivatives and Alkynes via Intramolecular Cleavage and Formation of the C−O Bond To Give 2,3-Disubstituted Benzofurans Shohei Ohno, Jiawei Qiu, Ray Miyazaki, Hiroshi Aoyama, Kenichi Murai, Jun-ya Hasegawa, and Mitsuhiro Arisawa Org. Lett. 2019, 21, 8400–8403. DOI: 10.1021/acs.orglett.9b03170.  |
| 14 | Design and Synthesis of a Phenyl C-Glycoside Derivative of Spliceostatin A and its Biological Evaluation toward Prostate Cancer Treatment Yusuke Yoshikawa, Airi Ishibashi, Kenichi Murai, Yasufumi Kaneda, Keisuke Nimura*, and Mitsuhiro Arisawa* Tetrahedron Lett. 2019, 60, 151313-151316. DOI: 10.1016/j.tetlet.2019.151313  |
| 15 | Direct Synthesis of Dialkylaryl-vinylsilane Derivatives: Metathesis of Dialkylaryl-iso-propenylsilane and Its Application to Tetracyclic Silacycle Dye Synthesis Shohei Yoshioka, Tsunayoshi Takehara, Tsuyoshi Matsuzaki, Takeyuki Suzuki, Hirofumi Tsujino, Tadayuki Uno, Yasuo Tsutsumi, Kenichi Murai, Hiromichi Fujioka, and Mitsuhiro Arisawa* Chem. Commun. 2019, 55, 14070-14073. DOI: 10.1039/C9CC06777A  |
| II. | Review |
| 1 | Development of Metal Nanoparticle Catalysis toward Drug Discovery(Invited Riviews) Mitsuhiro Arisawa Chem. Pharm. Bull., 2019, 67, 733-771.  |
| 2 | 連続照射マイクロ波を用いる有機合成化学 (Invited Riviews) 山田真希人、秋山敏毅、村井健一、有澤光弘 生産と技術、2019, 71, 70-73. |
| 3 | 画期的な触媒の開発で新しい薬の作り方やシーズを提案 (One Hour Inverview) 有澤光弘 HARIMA QUARTERLY, 2019, 139, 6-9. |
| 4 | 再利用可能なフォトレドックス触媒を用いたチオールの直接的アリール化 秋山敏毅 ファルマシア, 2019, 55, 568. |
| 5 | 後周期遷移金属錯体のβー炭素脱離による炭素ー炭素結合の活性化反応 大野祥平 有機合成化学協会誌, 2019, 77, 722-723. |
| 6 | イースト菌SF3B1複合体を用いたスプライシング阻害評価 吉川祐介 ファルマシア, 2019, 55, 977. |
| Ⅲ. | Winning Prize |