大阪大学薬学部　医薬合成化学分野

2024 Publications

Ⅰ. Paper

1	Synthesizing Silyl Arylsulfonyl Hydrazones as Silyldiazomethane Precursors and Their Use in Rhodium-catalyzed Reactions Shuji Tsuruda, Keigo Saito, Tsuyoshi Matsuzaki, Da-Yang Zhou, Takeyuki Suzuki, Makoto Sako, Mitsuhiro Arisawa, Kenichi Murai Adv. Synth. Catal. 2024, 366, 2305-2311. [Very Important Publicationに選出] DOI: 10.1002/adsc.202400172
2	Impact of Helical Elongation of Symmetric Oxa[n]helicenes on their Structural, Photophysical, and Chiroptical Characteristics Mohamed S. H. Salem, Rubal Sharma, Seika Suzuki, Yoshitane Imai, Mitsuhiro Arisawa, Shinobu Takizawa* Chirality 2024, 36, e23673. DOI: 10.1002/chir.23673
3	Chemical Constituents and Anticancer Activities of Marine-Derived Fungus Trichoderma lixii Natchanun Sirimangkalakitti, Jianyu Lin, Kazuo Harada, Andi Setiawan, Mitsuhiro Arisawa, Masayoshi Arai Molecules 2024, 29, 2048. (INVITED) DOI: 10.3390/molecules29092048
4	Brønsted acid-catalyzed synthesis of spirocyclobutanes via heteroannulation of vinyloxyphenylbicyclobutanes with water Masaharu Takatsuki, Hiroshi Aoyama, Mitsuhiro Arisawa, Makoto Sako Org. Biomol. Chem. 2024, 22, 4727-4731. DOI: 10.1039/D4OB00451E
5	Total Synthesis and Antibacterial Activity of Marine Tris-indole Alkaloid Tulongicin A Shuji Tsuruda, Takumi Sato, Hiroshi Aoyama, Natchanun Sirimangkalakitti, Shigeru Fujimura, Mitsuhiro Arisawa, Kenichi Murai J. Nat. Prod. 2024, 87, 1556-1562. DOI: 10.1021/acs.jnatprod.4c00129 ※本研究は東北医科薬科大学・薬学部の藤村茂先生との共同研究です。
6	Enantioselective Synthesis of Secondary Amines by Combining Oxidative Rearrangement and Biocatalysis in a One-Pot Process Laura M. Bernhard, Kateryna Zelenska, Mirei Takashima, Mitsuhiro Arisawa, Kenichi Murai, Harald Gröger* J. Org. Chem. 2024, 89, 8513-8520. DOI: 10.1021/acs.joc.4c00459
7	Oxidative Rearrangement Approach for the Ring Contraction of N–H Piperidines to Pyrrolidine Mirei Takashima, Makoto Miyoshi, Makoto Sako, Mitsuhiro Arisawa, Kenichi Murai Adv. Synth. Catal. 2024, 366, 3325-3331. [Very Important Publicationに選出] DOI: 10.1002/adsc.202400484
8	Absorption, Fluorescence, and Two-Photon Excitation Ability of 5-o-Tolyl-11 (or 13)-o-tolylisoindolo[2,1-a]quinolines Prepared by Ring-Closing Metathesis and [2+3] Cycloaddition Yuki Wada, Kwangkyun Jang, Hirokazu Ishii, Yuki Watakabe, Motosuke Tsutsumi, Makoto Sako, Tsunayoshi Takehara, Takeyuki Suzuki, Hirofumi Tsujino, Yasuo Tsutsumi, Tomomi Nemoto, Mitsuhiro Arisawa* Chem. Asian J. 2024, in press (INVITED). DOI: org/10.1002/asia.202401073 （本研究は生理学研究所・大阪大学SANKENとの共同研究です）
9	Multi-task Rhodium-Catalyzed Remote C(sp3)–H Functionalization Reactions of Acyclic Dienes to Yield Benzene-fused Heterocycles Yuta Sato, Momoko Nagafuchi, Masaharu Takatsuki, Tsuyoshi Matsuzaki, Takeyuki Suzuki, Makoto Sako, Mitsuhiro Arisawa* Green Chem. 2024, in press. DOI: 10.1039/D4GC04927F
10	Synthesis of Dibenzoxasilepine Using Ring Expansion Reaction of a Pentacoordinate Silicon Intermediate Keigo Watanabe, Mutsuki Sato, Tsunayoshi Takehara, Kaori Asano, Tsuyoshi Matsuzaki, Takeyuki Suzuki, Makoto Sako, Mitsuhiro Arisawa* Adv. Synth. Catal. 2024, in press. DOI: 10.1002/adsc.202401125
11
12

II. Review

1	低分子化合物の高度化研究：環状ケイ素化合物新規合成法の開発とその生物活性有澤光弘* 生産と技術 2024, 76(2), 49-52. (INVITED) http://seisan.server-shared.com/762/762-49.pdf
2	不斉リモート炭素（sp3）-水素アリール化有澤光弘* 科学と工業. 2024, 77, 738.(INVITED) https://www.chemistry.or.jp/division-topics/2024/09/sp3-.html

III. Winning Prize

1	日本薬学会第144年会学生優秀発表賞中原さん（B6）が日本薬学会第144年会で優秀発表賞（ポスター発表）を受賞しました。
2	2024年度有機合成化学北陸セミナーポスター賞関口さん（D1）が2024年度有機合成化学北陸セミナーでポスター賞を受賞しました。
3	令和６年度大阪大学賞（若手教員部門）佐古助教が令和６年度大阪大学賞（若手教員部門）を受賞しました。